By crossing lipodystrophy mice (A-ZIP/F1) with mice expressing a dominant negative MSTN receptor (activin receptor type IIB) in muscle, inhibition of MSTN action in A-ZIP/F1 mice notably lower the levels of blood glucose, serum insulin, triglyceride, and triglyceride synthesis rate, and enhanced insulin sensitivity (66)
J., Li, H., Kim, M., DAgati, V
A Trojan horse technique to facilitate BBB penetration of stabilized glycosylated polymeric siRNA nanomedicine (Gal-NP@siRNA) in transgenic mice model was explored (97)
Pea-Gallego et al., 2012) or as conjugated oxylipins upon leaf infiltration of keto-fatty acids (Davoine et al., 2005)
These properties underpin MT3s critical role in neuronal copper buffering and oxidative defense (150, 163)